Beware of Wordpress 2.6. I just upgraded and lost all my categories. If you are adventurous, I would suggest backing up your database before proceeding.
BloggingAmigos
Friends sharing their blogging experience
Friends sharing their blogging experience
I would suggest backing up before doing any upgrade
While I agree with Smitty and Chalupa - you should always back up before upgrading - I didn’t have any trouble at all.